– Dr. McIvor, Chief Development Officer, to present on the Sleeping Beauty-Engineered B Lymphocytes ISP™ platform –
WIRE) –September 10, 2019– Immusoft Corporation, a Seattle-Wash.-based,
leading cell therapy company, today announced that Scott McIvor, Ph.D., Chief Development
Officer, and Professor Genetics, Cell Biology, and Development at the
University of Minnesota, will present at the 2nd International
Conference on Lymphocyte Engineering (ICLE 2019), hosted in London, UK,
September 13 – 15, 2019.
Dr. McIvor will present, “Sleeping
Beauty-Engineered B Lymphocytes as Cellular Vehicles for Expression of Therapeutic
Proteins,” during the Non-Viral Vectors and Transposons session at 8:50 a.m. BST
/ 12:50 a.m. PT on Saturday, September 14, 2019.
With over 150 publications, Dr. McIvor is one of
the earliest pioneers in gene transfer and gene therapy. Dr. McIvor received
his Ph.D. in Microbiology from the University of Minnesota in 1982. He completed
his postdoctoral work at the University of California, San Francisco, and then
at Genentech, Inc., where he conducted early work on therapeutic gene transfer
into mouse hematopoietic stem cells using retroviral vectors. Dr. McIvor has
been on the faculty at the University of Minnesota since 1986, where he has
worked on the development of genetic therapies for cancer and inherited
metabolic and immunodeficiency diseases using viral and non-viral vector
systems. Starting in 2006, Dr. McIvor was CEO and Chief Science Officer of
Discovery Genomics, Inc. (DGI), founded in part to develop the Sleeping Beauty
transposon system. In 2016, DGI was acquired by Immusoft Corporation where Dr.
McIvor currently serves as Chief Development Officer. Dr. McIvor also served on
the NIH Recombinant DNA Advisory Committee and is an industry-recognized key
thought leader for lysosomal storage disorders.
Additional information regarding the ISP™ platform and the ICLE 2019 presentation can be found at: https://immusoft.com/technology/.
About ICLE London 2019
The International Conference on
Lymphocyte Engineering 2019 (ICLE) will be hosted in London, UK from September
13-15, 2019. ICLE 2019 is the place where the world`s health innovators come
together to discuss the challenges and opportunities in the field of
immuno-gene therapy. ICLE London 2019 will host the only community across
industry and academia dedicated to lymphocyte engineering. For more
About Immune System Programming (ISP™) Technology
Immusoft’s proprietary ISP™ platform
technology is a gene modified cell therapy approach that uses a clinically
validated, non-viral vector that aims to safely and reliably insert functional
genes into immune cells. Once administered back into the patient, a subset of
ISP™ modified cells are expected to reside within survival niches in the body,
continuously producing gene-encoded protein(s). The platform’s broad utility to
produce a wide range of therapeutic protein classes (e.g. antibodies, signaling
proteins, and enzymes), has the potential to disrupt the current standard of
care for many diseases requiring protein injections or infusions, including
many to address orphan diseases.
About Mucopolysaccharidosis type I (MPS I)
MPS I is a rare, lethal childhood
genetic disease that affects the body’s ability to produce IDUA
(alpha-L-iduronidase), which is an essential enzyme that helps to break down
long-chain sugars inside cells. When the sugar chains cannot be broken down and
disposed of, they accumulate in the cells and cause progressive damage. In its
most severe form, and if left untreated, children affected rarely live longer
than ten years after diagnosis.
(immusoft.com) mission is to treat diseases using its breakthrough technology
platform called Immune System Programming (ISP™). The technology modifies a
patient’s B cells and instructs the cells to produce gene-encoded medicines
(biologics). The B cells that are reprogrammed using ISP become miniature drug
factories that are expected to survive in patients for many years. Immusoft Corporation
is based in Seattle, Washington.
Media & Investors
Glenn Schulman, PharmD, MPH
Z3 Biocommunications, LLC
Immusoft makes history with the first engineered B cell investigational therapy cleared for human trials Immusoft seeks to improve the treatment of MPS I, a rare childhood disease, through the use of its Immune System Programming (ISP™) approach that utilizes B cells as re-dosable biofactories…